Type I Interferon Drives Dendritic Cell Apoptosis via Multiple BH3-Only Proteins following Activation by PolyIC In Vivo

BACKGROUND: DC are activated by pathogen-associated molecular patterns (PAMPs), and this is pivotal for the induction of adaptive immune responses. Thereafter, the clearance of activated DC is crucial to prevent immune pathology. While PAMPs are of major interest for vaccine science due to their adj...

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Detalles Bibliográficos
Autores principales: Fuertes Marraco, Silvia A., Scott, Clare L., Bouillet, Philippe, Ives, Annette, Masina, Slavica, Vremec, David, Jansen, Elisa S., O'Reilly, Lorraine A., Schneider, Pascal, Fasel, Nicolas, Shortman, Ken, Strasser, Andreas, Acha-Orbea, Hans
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107228/
https://ncbi.nlm.nih.gov/pubmed/21674051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020189
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