Type I Interferon Drives Dendritic Cell Apoptosis via Multiple BH3-Only Proteins following Activation by PolyIC In Vivo

BACKGROUND: DC are activated by pathogen-associated molecular patterns (PAMPs), and this is pivotal for the induction of adaptive immune responses. Thereafter, the clearance of activated DC is crucial to prevent immune pathology. While PAMPs are of major interest for vaccine science due to their adj...

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Autors principals: Fuertes Marraco, Silvia A., Scott, Clare L., Bouillet, Philippe, Ives, Annette, Masina, Slavica, Vremec, David, Jansen, Elisa S., O'Reilly, Lorraine A., Schneider, Pascal, Fasel, Nicolas, Shortman, Ken, Strasser, Andreas, Acha-Orbea, Hans
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107228/
https://ncbi.nlm.nih.gov/pubmed/21674051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020189
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