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Chemoselective Small Molecules that Covalently Modify One Lys in a Non-enzyme Protein in Plasma

A small molecule that could bind selectively to and then react chemoselectively with a non-enzyme protein in a complex biological fluid, such as blood, could have numerous practical applications. Herein, we report a family of designed stilbenes that selectively and covalently modify the prominent pl...

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Detalhes bibliográficos
Main Authors: Choi, Sungwook, Connelly, Stephen, Reixach, Natàlia, Wilson, Ian A., Kelly, Jeffery W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107129/
https://ncbi.nlm.nih.gov/pubmed/20081815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.281
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