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Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decay

The main reason why tumours are not controlled by the immune system is that, unlike pathogens, they do not express potent tumour rejection antigens (TRAs). Tumour vaccination aims at stimulating a systemic immune response targeted to, mostly weak, antigens expressed in the disseminated tumour lesion...

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Detalhes bibliográficos
Main Authors: Pastor, Fernando, Kolonias, Despina, Giangrande, Paloma H., Gilboa, Eli
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107067/
https://ncbi.nlm.nih.gov/pubmed/20463739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08999
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