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Cloning of Two Human Homologs of the Drosophila single-minded Gene SIM1 on Chromosome 6q and SIM2 on 21q Within the Down Syndrome Chromosomal Region

As part of our effort to clone genes of human chromosome 21 that may contribute to Down syndrome, we have previously isolated four exons with homology to Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of fruit fly neurogenesis. These exons were u...

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Main Authors: Chrast, Roman, Scott, Hamish S., Chen, Haiming, Kudoh, Jun, Rossier, Colette, Minoshima, Shinsei, Wang, Yimin, Shimizu, Nobuyoshi, Antonarakis, Stylianos E.
פורמט: Artigo
שפה:Inglês
יצא לאור: Cold Spring Harbor Laboratory Press 1997
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC310662/
https://ncbi.nlm.nih.gov/pubmed/9199934
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