The Mouse Brain Transcriptome by SAGE: Differences in Gene Expression between P30 Brains of the Partial Trisomy 16 Mouse Model of Down Syndrome (Ts65Dn) and Normals

Trisomy 21, or Down syndrome (DS), is the most common genetic cause of mental retardation. Changes in the neuropathology, neurochemistry, neurophysiology, and neuropharmacology of DS patients' brains indicate that there is probably abnormal development and maintenance of central nervous system...

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Autori principali: Chrast, Roman, Scott, Hamish S., Papasavvas, Marie Pierre, Rossier, Colette, Antonarakis, Emmanuel S., Barras, Christine, Davisson, Muriel T., Schmidt, Cecilia, Estivill, Xavier, Dierssen, Mara, Pritchard, Melanie, Antonarakis, Stylianos E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2000
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Letter
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC313062/
https://ncbi.nlm.nih.gov/pubmed/11116095
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