Luteolin induces hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome

Studies have shown that the natural flavonoid luteolin has neurotrophic activity. In this study, we investigated the effect of luteolin in a mouse model of Down syndrome. Ts65Dn mice, which are frequently used as a model of Down syndrome, were intraperitoneally injected with 10 mg/kg luteolin for 4...

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主要な著者:	Wen-Bo Zhou, Zong-Ning Miao, Bin Zhang, Wei Long, Fang-Xiu Zheng, Jing Kong, Bin Yu
フォーマット:	Artigo
言語:	Inglês
出版事項:	Wolters Kluwer Medknow Publications 2019-01-01
シリーズ:	Neural Regeneration Research
主題:	nerve regeneration; luteolin; hippocampus; Ts65Dn mice; neurogenesis; ERK; BDNF; nestin; GFAP; NeuN; Down syndrome; neural regeneration
オンライン･アクセス:	http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=4;spage=613;epage=620;aulast=Zhou
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