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Deleterious Effects of Chronic Folate Deficiency in the Ts65Dn Mouse Model of Down Syndrome

Folate is an important B vitamin naturally found in the human diet and plays a critical role in methylation of nucleic acids. Indeed, abnormalities in this major epigenetic mechanism play a pivotal role in the pathogenesis of cognitive deficit and intellectual disability in humans. The most common c...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Susan Helm, Morgan Blayney, Taylor Whited, Mahjabin Noroozi, Sen Lin, Semira Kern, David Green, Ahmad Salehi
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2017-06-01
Rangatū:Frontiers in Cellular Neuroscience
Ngā marau:
Urunga tuihono:http://journal.frontiersin.org/article/10.3389/fncel.2017.00161/full
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