Neuroanatomical alterations and synaptic plasticity impairment in the perirhinal cortex of the Ts65Dn mouse model of Down syndrome

Down syndrome (DS), a genetic condition due to triplication of Chromosome 21, is characterized by numerous neurodevelopmental alterations and intellectual disability. Individuals with DS and DS mouse models are impaired in several memory domains, including hippocampus-dependent declarative (spatial,...

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Bibliografski detalji

Glavni autori:	Vincenzo Roncacé, Costanza Burattini, Fiorenza Stagni, Sandra Guidi, Andrea Giacomini, Marco Emili, Giorgio Aicardi, Renata Bartesaghi
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2017-10-01
Serija:	Neurobiology of Disease
Teme:	Down syndrome Memory impairment Ts65Dn model Perirhinal cortex Synaptic function GIRK2
Online pristup:	http://www.sciencedirect.com/science/article/pii/S0969996117301432
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