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INTERFERON-ALPHA MEDIATES THE DEVELOPMENT OF AUTOIMMUNITY BOTH BY DIRECT TISSUE TOXICITY AND THROUGH IMMUNE-CELL RECRUITMENT MECHANISMS
Interferon alpha (IFNα) is known to play a key role in autoimmunity, but the mechanisms are uncertain. Although the induction of autoimmunity by IFNα is consistent with primarily immuno-modulatory effects, the high frequency of non-autoimmune inflammation suggests other mechanisms. We used thyroidit...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3106338/ https://ncbi.nlm.nih.gov/pubmed/21402899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002631 |
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