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HCV E2 PROTEIN BINDS DIRECTLY TO THYROID CELLS AND INDUCES IL-8 PRODUCTION: A NEW MECHANISM FOR HCV INDUCED THYROID AUTOIMMUNITY

HCV infection is well-known to be associated with autoimmune thyroiditis. However, the mechanisms by which HCV triggers thyroiditis are unknown. We hypothesized that HCV envelope proteins could induce thyroidal inflammation directly, thereby triggering thyroiditis by bystander activation mechanism....

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Detalhes bibliográficos
Main Authors: Akeno, Nagako, Blackard, Jason T., Tomer, Yaron
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2641008/
https://ncbi.nlm.nih.gov/pubmed/18799285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2008.08.001
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