Design and specificity of hammerhead ribozymes against calretinin mRNA.
We obtained a partial sequence of mouse calretinin mRNA from cDNA clones, and designed hammerhead ribozymes to cleave positions within it. With a view to optimising hammerhead ribozymes for eliminating the mRNA in vivo, we varied the length and sequence of the three duplex 'arms' and measured the cl...
সংরক্ষণ করুন:
| প্রকাশিত: | Nucleic Acids Res |
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| প্রধান লেখক: | , |
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
Oxford University Press
1993
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| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310633/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8255773/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.22.5171 |
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