Design and specificity of hammerhead ribozymes against calretinin mRNA.
We obtained a partial sequence of mouse calretinin mRNA from cDNA clones, and designed hammerhead ribozymes to cleave positions within it. With a view to optimising hammerhead ribozymes for eliminating the mRNA in vivo, we varied the length and sequence of the three duplex 'arms' and measured the cl...
में बचाया:
| में प्रकाशित: | Nucleic Acids Res |
|---|---|
| मुख्य लेखकों: | , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Oxford University Press
1993
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| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310633/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8255773/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.22.5171 |
| टैग: |
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