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Short-term fasting induces profound neuronal autophagy

Disruption of autophagy—a key homeostatic process in which cytosolic components are degraded and recycled through lysosomes—can cause neurodegeneration in tissue culture and in vivo. Upregulation of this pathway may be neuroprotective, and much effort is being invested in developing drugs that cross...

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Autori principali: Alirezaei, Mehrdad, Kemball, Christopher C., Flynn, Claudia T., Wood, Malcolm R., Whitton, J. Lindsay, Kiosses, William B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3106288/
https://ncbi.nlm.nih.gov/pubmed/20534972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.6.6.12376
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