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Single exchanges of amino acids in the basic region change the specificity of N-Myc.

We exchanged specific amino acids in the basic region of the murine N-Myc protein and tested the mutant proteins for their DNA binding specificity. The amino acids we exchanged were chosen in analogy to residues of the homologous basic regions of bHLH and bZIP proteins. Mutant N-Myc peptides were ex...

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Udgivet i:Nucleic Acids Res
Principais autores: Feldmann, T, Alex, R, Suckow, J, Dildrop, R, Kisters-Woike, B, Müller-Hill, B
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1993
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310616/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7902977/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.22.5050
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