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JNK1 deficiency limits macrophage mediated antigen-induced arthritis

OBJECTIVE: To elucidate the non-redundant roles of JNK1 and JNK2 in antigen-induced arthritis (AIA). METHODS: Mice that were genetically disrupted in Jnk1 or Jnk2 were primed with methylated BSA (mBSA) in complete Freund’s adjuvant and then given an intraarticular challenge with mBSA in the knee on...

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Hlavní autoři: Guma, Monica, Ronacher, Lisa M., Firestein, Gary S., Karin, Michael, Corr, Maripat
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3106119/
https://ncbi.nlm.nih.gov/pubmed/21305529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.30271
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