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JNK1 deficiency limits macrophage mediated antigen-induced arthritis

OBJECTIVE: To elucidate the non-redundant roles of JNK1 and JNK2 in antigen-induced arthritis (AIA). METHODS: Mice that were genetically disrupted in Jnk1 or Jnk2 were primed with methylated BSA (mBSA) in complete Freund’s adjuvant and then given an intraarticular challenge with mBSA in the knee on...

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Detalhes bibliográficos
Main Authors: Guma, Monica, Ronacher, Lisa M., Firestein, Gary S., Karin, Michael, Corr, Maripat
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3106119/
https://ncbi.nlm.nih.gov/pubmed/21305529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.30271
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