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Expanding the Understanding of Biases in Development of Clinical-Grade Molecular Signatures: A Case Study in Acute Respiratory Viral Infections

BACKGROUND: The promise of modern personalized medicine is to use molecular and clinical information to better diagnose, manage, and treat disease, on an individual patient basis. These functions are predominantly enabled by molecular signatures, which are computational models for predicting phenoty...

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Main Authors: Lytkin, Nikita I., McVoy, Lauren, Weitkamp, Jörn-Hendrik, Aliferis, Constantin F., Statnikov, Alexander
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105991/
https://ncbi.nlm.nih.gov/pubmed/21673802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020662
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