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Expanding the Understanding of Biases in Development of Clinical-Grade Molecular Signatures: A Case Study in Acute Respiratory Viral Infections

BACKGROUND: The promise of modern personalized medicine is to use molecular and clinical information to better diagnose, manage, and treat disease, on an individual patient basis. These functions are predominantly enabled by molecular signatures, which are computational models for predicting phenoty...

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Autori principali: Lytkin, Nikita I., McVoy, Lauren, Weitkamp, Jörn-Hendrik, Aliferis, Constantin F., Statnikov, Alexander
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105991/
https://ncbi.nlm.nih.gov/pubmed/21673802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020662
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