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Expanding the Understanding of Biases in Development of Clinical-Grade Molecular Signatures: A Case Study in Acute Respiratory Viral Infections

BACKGROUND: The promise of modern personalized medicine is to use molecular and clinical information to better diagnose, manage, and treat disease, on an individual patient basis. These functions are predominantly enabled by molecular signatures, which are computational models for predicting phenoty...

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Detalhes bibliográficos
Main Authors: Lytkin, Nikita I., McVoy, Lauren, Weitkamp, Jörn-Hendrik, Aliferis, Constantin F., Statnikov, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105991/
https://ncbi.nlm.nih.gov/pubmed/21673802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020662
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