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Control of human β-globin mRNA stability and its impact on beta-thalassemia phenotype
Messenger RNA (mRNA) stability is a critical determinant that affects gene expression. Many pathways have evolved to modulate mRNA stability in response to developmental, physiological and/or environmental stimuli. Eukaryotic mRNAs have a considerable range of half-lives, from as short as a few minu...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Ferrata Storti Foundation
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3105653/ https://ncbi.nlm.nih.gov/pubmed/21357703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.039206 |
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