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Relative stability of alpha- and beta-globin messenger RNAs in homozygous beta+ thalassemia.

The relative concentrations of alpha-, beta-, and gamma-globin mRNA sequences were measured in bone marrow nuclear and cytoplasmic RNA and in RNA from peripheral blood reticulocytes of three patients with homozygous beta+ thalassemia. Our results suggest that the quantitative deficiency in beta-glob...

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Main Authors: Nienhuis, A W, Turner, P, Benz, E J
Formato: Artigo
Idioma:Inglês
Publicado em: 1977
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC431801/
https://ncbi.nlm.nih.gov/pubmed/71735
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