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Relative stability of alpha- and beta-globin messenger RNAs in homozygous beta+ thalassemia.

The relative concentrations of alpha-, beta-, and gamma-globin mRNA sequences were measured in bone marrow nuclear and cytoplasmic RNA and in RNA from peripheral blood reticulocytes of three patients with homozygous beta+ thalassemia. Our results suggest that the quantitative deficiency in beta-glob...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Nienhuis, A W, Turner, P, Benz, E J
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1977
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431801/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/71735/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.9.3960
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