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Authentic beta-globin mRNA sequences in homozygous betaO-thalassemia.

In a patient with homozygous betaO-thalassemia in whom studies of reticulocyte hemoglobin synthesis showed no beta-globin chain synthesis in vivo and in vitro, molecular hybridization studies revealed RNA sequences complementary to beta-globin cDNA. The fact that these sequences were authentic beta-...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Temple, G F, Chang, J C, Kan, Y W
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1977
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC431405/
https://ncbi.nlm.nih.gov/pubmed/268654
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