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Control of human β-globin mRNA stability and its impact on beta-thalassemia phenotype

Messenger RNA (mRNA) stability is a critical determinant that affects gene expression. Many pathways have evolved to modulate mRNA stability in response to developmental, physiological and/or environmental stimuli. Eukaryotic mRNAs have a considerable range of half-lives, from as short as a few minu...

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Hlavní autoři: Peixeiro, Isabel, Silva, Ana Luísa, Romão, Luísa
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105653/
https://ncbi.nlm.nih.gov/pubmed/21357703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.039206
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