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Novel mechanism of regulation of the DNA repair enzyme OGG1 in tuberin-deficient cells

Tuberin (protein encodes by tuberous sclerosis complex 2, Tsc2) deficiency is associated with the decrease in the DNA repair enzyme 8-oxoG-DNA glycosylase (OGG1) in tumour kidney of tuberous sclerosis complex (TSC) patients. The purpose of this study was to elucidate the mechanisms by which tuberin...

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Autores principales: Habib, Samy L., Bhandari, Besant K., Sadek, Nahed, Abboud-Werner, Sherry L., Abboud, Hanna E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105579/
https://ncbi.nlm.nih.gov/pubmed/20837600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq189
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