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The molecular and cellular basis of variable craniofacial phenotypes and their genetic rescue in Twisted gastrulation mutant mice

The severity of numerous developmental abnormalities can vary widely despite shared genetic causes. Mice deficient in Twisted gastrulation (Twsg1(−/−)) display such phenotypic variation, developing a wide range of craniofacial malformations on an isogenic C57BL/6 strain background. To examine the mo...

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Библиографические подробности
Главные авторы: Billington, Charles J., Ng, Brandon, Forsman, Cynthia, Schmidt, Brian, Bagchi, Anindya, Symer, David E., Schotta, Gunnar, Gopalakrishnan, Rajaram, Sarver, Aaron L., Petryk, Anna
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105466/
https://ncbi.nlm.nih.gov/pubmed/21549111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.04.026
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