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U1 adaptors result in reduction of multiple pre-mRNA species principally by sequestering U1snRNP
U1 Adaptors are a recently reported novel approach for targeted reduction of mRNA transcripts. A U1 adaptor oligonucleotide comprising of a target-complimentary hybridization domain and a U1 recruitment domain, directs the U1 snRNP complex to the terminal exon of a targeted gene, subsequently inhibi...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3105408/ https://ncbi.nlm.nih.gov/pubmed/21415007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr150 |
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