TEFM (c17orf42) is necessary for transcription of human mtDNA

Here we show that c17orf42, hereafter TEFM (transcription elongation factor of mitochondria), makes a critical contribution to mitochondrial transcription. Inactivation of TEFM in cells by RNA interference results in respiratory incompetence owing to decreased levels of H- and L-strand promoter-dist...

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Detalhes bibliográficos
Main Authors: Minczuk, Michal, He, Jiuya, Duch, Anna M., Ettema, Thijs J., Chlebowski, Aleksander, Dzionek, Karol, Nijtmans, Leo G. J., Huynen, Martijn A., Holt, Ian J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105396/
https://ncbi.nlm.nih.gov/pubmed/21278163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1224
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