Activity of hammerhead ribozymes containing non-nucleotidic linkers.
Hammerhead ribozymes were synthesized in which the tetranucleotide loop II was replaced by non-nucleotidic linkers of 7, 13, 17 and 19 atoms length. Ribozymes with 17 and 19 atom linkers, in combination with a 4 base pair stem II, had catalytic efficiencies which were 2 fold increased to that of the...
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| Udgivet i: | Nucleic Acids Res |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1993
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310522/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7506829/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.24.5600 |
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