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Activity of hammerhead ribozymes containing non-nucleotidic linkers.

Hammerhead ribozymes were synthesized in which the tetranucleotide loop II was replaced by non-nucleotidic linkers of 7, 13, 17 and 19 atoms length. Ribozymes with 17 and 19 atom linkers, in combination with a 4 base pair stem II, had catalytic efficiencies which were 2 fold increased to that of the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Thomson, J B, Tuschl, T, Eckstein, F
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1993
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC310522/
https://ncbi.nlm.nih.gov/pubmed/7506829
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