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Interaction of tyrosine 151 in norepinephrine transporter with the 2β group of cocaine analog RTI-113
Cocaine binds and inhibits dopamine transporter (DAT), norepinephrine transporter (NET) and serotonin transporter. The residues forming cocaine binding sites are unknown. RTI-113, a cocaine analog, is 100x more potent at inhibiting DAT than inhibiting NET. Here we show that removing the hydroxyl gro...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3105219/ https://ncbi.nlm.nih.gov/pubmed/21420984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2011.03.014 |
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