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Functional mutations in mouse norepinephrine transporter reduce sensitivity to cocaine inhibition

The transporters of dopamine, norepinephrine and serotonin are molecular targets of cocaine, amphetamine, and therapeutic antidepressants. The residues involved in binding these drugs are unknown. We have performed several rounds of random and site-directed mutagenesis in the mouse norepinephrine tr...

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Autors principals: Wei, Hua, Hill, Erik R, Gu, Howard H.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666010/
https://ncbi.nlm.nih.gov/pubmed/18824182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2008.09.008
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