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Specific transcriptional activation in vitro by the herpes simplex virus protein VP16.

The herpes simplex virus protein VP16 interacts with cellular factors, including the protein Oct-1, to activate viral immediate early (IE) gene transcription. We have reproduced this effect by addition of purified, full-length VP16 and the DNA-binding 'POU' domain of Oct-1 (Oct-1/POU) to a HeLa cell...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Arnosti, D N, Preston, C M, Hagmann, M, Schaffner, W, Hope, R G, Laughlan, G, Luisi, B F
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 1993
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310517/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8284200/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.24.5570
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