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Specific transcriptional activation in vitro by the herpes simplex virus protein VP16.

The herpes simplex virus protein VP16 interacts with cellular factors, including the protein Oct-1, to activate viral immediate early (IE) gene transcription. We have reproduced this effect by addition of purified, full-length VP16 and the DNA-binding 'POU' domain of Oct-1 (Oct-1/POU) to a...

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Bibliografski detalji
Glavni autori: Arnosti, D N, Preston, C M, Hagmann, M, Schaffner, W, Hope, R G, Laughlan, G, Luisi, B F
Format: Artigo
Jezik:Inglês
Izdano: 1993
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC310517/
https://ncbi.nlm.nih.gov/pubmed/8284200
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