Specific transcriptional activation in vitro by the herpes simplex virus protein VP16.

The herpes simplex virus protein VP16 interacts with cellular factors, including the protein Oct-1, to activate viral immediate early (IE) gene transcription. We have reproduced this effect by addition of purified, full-length VP16 and the DNA-binding 'POU' domain of Oct-1 (Oct-1/POU) to a HeLa cell...

Полное описание

Библиографические подробности

Опубликовано в::	Nucleic Acids Res
Главные авторы:	Arnosti, D N, Preston, C M, Hagmann, M, Schaffner, W, Hope, R G, Laughlan, G, Luisi, B F
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Oxford University Press 1993
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310517/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8284200/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.24.5570
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