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Histone Deacetylase Inhibitors for Purging HIV-1 from the Latent Reservoir

A reservoir of latently infected memory CD4(+) T cells is believed to be the source of HIV-1 reemergence after discontinuation of antiretroviral therapy. HIV-1 eradication may depend on depletion of this reservoir. Integrated HIV-1 is inaccessible for expression, in part because of histone deacetyla...

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Detalhes bibliográficos
Main Authors: Matalon, Shay, Rasmussen, Thomas A, Dinarello, Charles A
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105138/
https://ncbi.nlm.nih.gov/pubmed/21424110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00076
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