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Selection Against Frameshift Mutations Limits Microsatellite Expansion in Coding DNA

Microsatellite enrichment is an excess of repetitive sequences characteristic to all studied eukaryotes. It is thought to result from the accumulated effects of replication slippage mutations. Enrichment is commonly measured as the ratio of the observed frequency of microsatellites to the frequency...

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Publicat a:Genome Res
Autors principals: Metzgar, David, Bytof, Jeffrey, Wills, Christopher
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2000
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310501/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10645952/
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