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Genetic Profile of Insertion Mutations in Mouse Leukemias and Lymphomas

Murine leukemia retroviruses (MuLVs) cause leukemia and lymphoma in susceptible strains of mice as a result of insertional mutation of cellular proto-oncogenes or tumor suppressor genes. Using a novel approach to amplify and sequence viral insertion sites, we have sequenced >200 viral insertion site...

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Bibliographic Details
Published in:Genome Res
Main Authors: Hansen, Gwenn M., Skapura, Darlene, Justice, Monica J.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2000
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310834/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10673281/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gr.10.2.237
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