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Selection Against Frameshift Mutations Limits Microsatellite Expansion in Coding DNA

Microsatellite enrichment is an excess of repetitive sequences characteristic to all studied eukaryotes. It is thought to result from the accumulated effects of replication slippage mutations. Enrichment is commonly measured as the ratio of the observed frequency of microsatellites to the frequency...

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Detalhes bibliográficos
Publicado no:Genome Res
Principais autores: Metzgar, David, Bytof, Jeffrey, Wills, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310501/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10645952/
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