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CD73 has distinct roles in nonhematopoietic and hematopoietic cells to promote tumor growth in mice

CD73 is overexpressed in many types of human and mouse cancers and is implicated in the control of tumor progression. However, the specific contribution from tumor or host CD73 expression to tumor growth remains unknown to date. Here, we show that host CD73 promotes tumor growth in a T cell–dependen...

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Detalhes bibliográficos
Main Authors: Wang, Long, Fan, Jie, Thompson, Linda F., Zhang, Yi, Shin, Tahiro, Curiel, Tyler J., Zhang, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104756/
https://ncbi.nlm.nih.gov/pubmed/21537079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45559
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