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CD73 on tumor cells impairs anti-tumor T cell responses: a novel mechanism of tumor-induced immune suppression

CD73, originally defined as a lymphocyte differentiation antigen, is thought to function as a co-signaling molecule on T lymphocytes and an adhesion molecule that is required for lymphocyte binding to endothelium. We show here that CD73 is widely expressed on many tumor cell lines and is upregulated...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Jin, Dachuan, Fan, Jie, Wang, Long, Thompson, Linda F., Liu, Aijie, Daniel, Benjamin J., Shin, Tahiro, Curiel, Tyler J., Zhang, Bin
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883609/
https://ncbi.nlm.nih.gov/pubmed/20179192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3109
תגים: הוספת תג
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