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One-Pot Synthesis of Nucleoside 5′-Triphosphates from Nucleoside 5′-H-Phosphonates

[Image: see text] Nucleoside 5′-triphosphates (NTPs) play key roles in biology and medicine. However, these compounds are notoriously difficult to synthesize. We describe a one-pot method to prepare NTPs from nucleoside 5′-H-phosphonate monoesters via pyridinium phosphoramidates, and we used this ap...

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Hlavní autoři: Sun, Qi, Edathil, Jocelyn P., Wu, Runzhi, Smidansky, Eric D., Cameron, Craig E., Peterson, Blake R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104733/
https://ncbi.nlm.nih.gov/pubmed/18393512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol8003029
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