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Oncogenic Ras/Src cooperativity in pancreatic neoplasia
Pancreas cancer is one of the most lethal malignancies and is characterized by activating mutations of Kras, present in 95% of patients. More than 60% of pancreatic cancers also display increased c-Src activity, which is associated with poor prognosis. Although loss of tumor suppressor function (for...
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| Autores principales: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3104672/ https://ncbi.nlm.nih.gov/pubmed/21242978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.589 |
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