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Identification of NEEP21 as a β-Amyloid Precursor Protein-Interacting Protein In Vivo That Modulates Amyloidogenic Processing In Vitro

Alzheimer's disease (AD) is an age-related neurodegenerative disease and the most common form of dementia. AD is pathologically characterized by the deposition of pathogenic Aβ peptides that are derived from larger integral membrane proteins, termed β-amyloid precursor proteins (APPs). In an at...

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Autors principals: Norstrom, Eric M., Zhang, Can, Tanzi, Rudolph, Sisodia, Sangram S.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104400/
https://ncbi.nlm.nih.gov/pubmed/21084623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4464-10.2010
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