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Upregulation of Alzheimer’s amyloid-β protein precursor in astrocytes both in vitro and in vivo
The amyloid cascade hypothesis of Alzheimer’s disease (AD) posits that amyloid-β (Aβ) protein accumulation underlies the pathogenesis of the disease by leading to formation of β-amyloid plaques, a pathologic hallmark of AD. Aβ is a proteolytic product of β-amyloid protein precursor (AβPP; APP), whic...
Shranjeno v:
| izdano v: | J Alzheimers Dis |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7571426/ https://ncbi.nlm.nih.gov/pubmed/32597805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-200128 |
| Oznake: |
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