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Exon 6 variants carried on systemic lupus erythematosus (SLE) risk haplotypes modulate IRF5 function
Interferon response factor 5 (IRF5) regulates innate immune responses to viral infection. IRF5 genetic variants have been shown to be strongly associated with risk for systemic lupus erythematosus (SLE). Functional roles of IRF5 exon 6 structural variants that occur as part of a SLE risk-associated...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3104271/ https://ncbi.nlm.nih.gov/pubmed/20695768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08916934.2010.491842 |
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