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Exon 6 variants carried on systemic lupus erythematosus (SLE) risk haplotypes modulate IRF5 function

Interferon response factor 5 (IRF5) regulates innate immune responses to viral infection. IRF5 genetic variants have been shown to be strongly associated with risk for systemic lupus erythematosus (SLE). Functional roles of IRF5 exon 6 structural variants that occur as part of a SLE risk-associated...

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Hlavní autoři: Wen, Feng, Ellingson, Sonja M., Kyogoku, Chieko, Peterson, Erik J., Gaffney, Patrick M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104271/
https://ncbi.nlm.nih.gov/pubmed/20695768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08916934.2010.491842
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