Genetic Variants Near TNFAIP3 on 6q23 are Associated with Systemic Lupus Erythematosus (SLE)

SLE is an autoimmune disease influenced by genetic and environmental components. We performed a genome-wide association scan (GWAS) and observed novel association evidence with a variant inTNFAIP3(rs5029939, P = 2.89×10(−12), OR = 2.29). We also found evidence of two independent signals of associati...

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Autori principali: Graham, Robert R., Cotsapas, Chris, Davies, Leela, Hackett, Rachel, Lessard, Christopher J., Leon, Joanlise M., Burtt, Noel P., Guiducci, Candace, Parkin, Melissa, Gates, Casey, Plenge, Robert M., Behrens, Timothy W., Wither, Joan E., Rioux, John D., Fortin, Paul R., Graham, Deborah Cunninghame, Wong, Andrew K., Vyse, Timothy J., Daly, Mark J., Altshuler, David, Moser, Kathy L., Gaffney, Patrick M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772171/
https://ncbi.nlm.nih.gov/pubmed/19165918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.200
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