Benzoxathiol derivative BOT-4-one suppresses L540 lymphoma cell survival and proliferation via inhibition of JAK3/STAT3 signaling

Persistently activated JAK/STAT3 signaling pathway plays a pivotal role in various human cancers including major carcinomas and hematologic tumors, and is implicated in cancer cell survival and proliferation. Therefore, inhibition of JAK/STAT3 signaling may be a clinical application in cancer therap...

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Detalhes bibliográficos
Main Authors: Kim, Byung Hak, Min, Yun Sook, Choi, Jung Sook, Baeg, Gyeong-Hun, Kim, Youngsoo, Shin, Jong Wook, Kim, Tae-Yoon, Ye, Sang-Kyu
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Biochemistry and Molecular Biology 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104254/
https://ncbi.nlm.nih.gov/pubmed/21499010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2011.43.5.035
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