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Structures of segments of α-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation
Aggregates of the protein α-synuclein are the main component of Lewy bodies, the hallmark of Parkinson's disease. α-Synuclein aggregates are also found in many human neurodegenerative diseases known as synucleinopathies. In vivo, α-synuclein associates with membranes and adopts α-helical confor...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Wiley Subscription Services, Inc., A Wiley Company
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3104229/ https://ncbi.nlm.nih.gov/pubmed/21462277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.630 |
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