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Exploring sequence requirements for C(3)/C(4) carboxylate recognition in the Pseudomonas aeruginosa cephalosporinase: Insights into plasticity of the AmpC β-lactamase

In Pseudomonas aeruginosa, the chromosomally encoded class C cephalosporinase (AmpC β-lactamase) is often responsible for high-level resistance to β-lactam antibiotics. Despite years of study of these important β-lactamases, knowledge regarding how amino acid sequence dictates function of the AmpC P...

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Detaylı Bibliyografya
Asıl Yazarlar: Drawz, Sarah M, Taracila, Magdalena, Caselli, Emilia, Prati, Fabio, Bonomo, Robert A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Wiley Subscription Services, Inc., A Wiley Company 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104225/
https://ncbi.nlm.nih.gov/pubmed/21404358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.612
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